Overview
adapted from R. Barstead and Williams et al., Genetics 131: 609-624, 1992
This method is used to establish linkage of a mutation to a particular chromosome cluster or arm. Its advantage over mapping with visible marker mutations is that you can test linkage to all the chromosomes simultaneously without having so many marker mutations present that the animals are sick and confusing to score. Also, it saves a generation, so it's faster.
Details
Details of this protocol, Mapping Mutants Using STS Polymorphisms, are located on a web site other than Biocompare Protocols.