Preparation Of SiRNAs From Drosophila Embryo Extracts - Subscription Required Protocol

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Title Preparation Of SiRNAs From Drosophila Embryo Extracts - Subscription Required
Source CSH Protocols; 2006; doi:10.1101/pdb.prot4325

Overview

siRNAs produced upon the addition of dsRNA to Drosophila embryo extract are enriched in a micrococcus-nuclease-resistant fraction. After proteinase K treatment and dephosphorylation with calf intestinal phosphatase, these siRNAs mediate efficient RNAi in vitro. By Luyun Huang, John Gledhill and Craig E. Cameron.

Details

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