Assay For Luciferase In Extracts Of Mammalian Cells - Subscription Required Protocol

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Title Assay For Luciferase In Extracts Of Mammalian Cells - Subscription Required
Source CSH Protocols; 2006; doi:10.1101/pdb.prot3642

Overview

In this protocol, cells transfected with a luciferase reporter plasmid are lysed in a detergent-containing buffer. Luciferase in the extract catalyzes an oxidation reaction in which D-luciferin is converted to oxyluciferin, with production of light at 556 nm that can be quantified in a luminometer. By Joseph Sambrook and David W. Russell.

Details

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